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Unigene ncbi unigene term
Ncbi Unigene Term, supplied by Unigene, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Article Title: Lacritin and Other Autophagy Associated Proteins in Ocular Surface Health
Article Snippet: Niemann-Pick disease type C1 is expressed in normal and keratoconus cornea, retina, and optic nerve (NEIBank), and in other organs widely (NCBI Unigene).

Article Title: Therapeutic acid ceramidase compositions and methods of making and using them
Article Snippet: TABLE 1 Exemplary Acid Ceramidase Family Members Homo sapiens (SEQ ID NO: 1) Caenorhabditis elegans (SEQ ID NO: 5) UniProt Q13510, Q9H715, Q96AS2 UniProt O45686 OMIM 228000 IntAct O45686 NCBI Gene 427 NCBI Gene 173120 NCBI RefSeq NP_808592, NP_004306 NCBI RefSeq NP_493173 NCBI RefSeq NM_177924, NM_004315 NCBI RefSeq NM_060772 NCBI UniGene 427 NCBI UniGene 173120 NCBI Accession Q13510, AAC73009, NCBI Accession O45686, CAB05556 AAC50907 Mus musculus (SEQ ID NO: 2) Danio rerio (SEQ ID NO: 6) UniProt Q9WV54, Q3U8A7, UniProt Q5XJR7 NCBI Gene 11886 NCBI Gene 450068 NCBI RefSeq NP_062708 NCBI RefSeq NP_001006088 NCBI RefSeq NM_019734 NCBI RefSeq NM_001006088 NCBI UniGene 11886 NCBI UniGene 450068 NCBI Accession AK151208, AK034204 NCBI Accession AAH83231, CB360968 Gallus gallus (SEQ ID NO: 3) Rattus norvegicus (SEQ ID NO: 7) UniProt Q5ZK58 UniProt Q6P7S1, Q9EQJ6 NCBI Gene 422727 NCBI Gene 84431 NCBI RefSeq NP_001006453 NCBI RefSeq NP_445859 NCBI RefSeq NM_001006453 NCBI RefSeq NM_053407 NCBI UniGene 422727 NCBI UniGene 84431 NCBI Accession CAG31885, AJ720226 NCBI Accession AAH61540, AF214647 Pan troglodytes (SEQ ID NO: 4) NCBI Gene 464022 NCBI RefSeq XP_519629 NCBI RefSeq XM_519629 NCBI UniGene 464022 The ceramidase mixture of the therapeutic composition may, in some embodiments, contain a greater amount of the inactive AC precursor than active AC.


Article Title: Sex chromosome evolution in snakes inferred from divergence patterns of two gametologous genes and chromosome distribution of sex chromosome-linked repetitive sequences
Article Snippet: Thus, this gene is ubiquitously expressed in tetrapod species, such as humans, mice, chickens, and X. tropicalis (NCBI UniGene).

Sequencing:

Article Title: CIZ1-F, an alternatively spliced variant of the DNA replication protein CIZ1 with distinct expression and localisation, is overrepresented in early stage common solid tumours
Article Snippet: .. Overall, CIZ1 -F transcript is approximately 50-fold lower than ‘total’ CIZ1 mRNA in cycling cells, which is broadly consistent with the frequency of expressed sequence tags in NCBI UniGene (accessed 03/03/2018), where 11 of 875 sequences (all from cancers) are CIZ1 -F. CIZ1 -RD and CIZ1 -AD levels remain relatively stable during proliferative growth, and slightly increase during growth rate decline caused by serum starvation. ..

Functional Assay:

Article Title: AutismKB 2.0: a knowledgebase for the genetic evidence of autism spectrum disorder
Article Snippet: .. To better demonstrate the functional aspects of ASD-related genes, extensive information, including their nucleotide and protein sequences, gene ontology (GO), expression profiles among tissues, regulatory information and pathway and disease-related information, was retrieved from online database, which included NCBI gene, NCBI GEO, NCBI Unigene, GO, OMIM, HGNC, Ensembl, Uniprot, BioGRID, BIND, HPRD, AlzGene, PDGene, SZGene, MGI, ZFIN, FB, BioGPS, Allen Brain Atlas, PRIDE, Peptide Atlas, dbPTM, miRWalk, Tarbase, NATs, CTD, PharmGKB and DrugBank. ..

Expressing:

Article Title: AutismKB 2.0: a knowledgebase for the genetic evidence of autism spectrum disorder
Article Snippet: .. To better demonstrate the functional aspects of ASD-related genes, extensive information, including their nucleotide and protein sequences, gene ontology (GO), expression profiles among tissues, regulatory information and pathway and disease-related information, was retrieved from online database, which included NCBI gene, NCBI GEO, NCBI Unigene, GO, OMIM, HGNC, Ensembl, Uniprot, BioGRID, BIND, HPRD, AlzGene, PDGene, SZGene, MGI, ZFIN, FB, BioGPS, Allen Brain Atlas, PRIDE, Peptide Atlas, dbPTM, miRWalk, Tarbase, NATs, CTD, PharmGKB and DrugBank. ..



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Unigene ncbi unigene est database
Metabolic analysis and database mining strategy. A total of 324 metabolic genes were chosen from three systems: Hcy (119), glucose-related (95), and Lipid (66 for triglyceride and 44 for cholesterol metabolism) from the <t>NCBI</t> database. The mRNA expression patterns of these genes were analyzed across 21 human and 20 mouse organs using the NCBI Unigene <t>EST</t> database. Organs were categorized based on gene enrichment levels. Hcy metabolites were measured in 6 mouse organs (heart, liver, lung, kidney, spleen, and brain) using LC-ESI-MS/MS. Simple linear regression analysis was conducted to identify genes responsive to Hcy metabolites. The responsive genes were then utilized to identify corresponsive metabolic changes, construct protein-protein interaction networks, and identify organ-specific metabolic features related to Hcy metabolites. Finally, genetic-metabolic models were established for how Hcy metabolites contribute to metabolic reprogramming, crosstalk, and oxidative stress. Abbreviations: Hcy, homocysteine; SAH, S-adenosylhomocysteine; SAM, S-adenosylmethionine; HM, homocysteine-methionine; CH, cholesterol; TG, triglyceride.
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Unigene ncbi unigene est profile
Metabolic analysis and database mining strategy. A total of 324 metabolic genes were chosen from three systems: Hcy (119), glucose-related (95), and Lipid (66 for triglyceride and 44 for cholesterol metabolism) from the <t>NCBI</t> database. The mRNA expression patterns of these genes were analyzed across 21 human and 20 mouse organs using the NCBI Unigene <t>EST</t> database. Organs were categorized based on gene enrichment levels. Hcy metabolites were measured in 6 mouse organs (heart, liver, lung, kidney, spleen, and brain) using LC-ESI-MS/MS. Simple linear regression analysis was conducted to identify genes responsive to Hcy metabolites. The responsive genes were then utilized to identify corresponsive metabolic changes, construct protein-protein interaction networks, and identify organ-specific metabolic features related to Hcy metabolites. Finally, genetic-metabolic models were established for how Hcy metabolites contribute to metabolic reprogramming, crosstalk, and oxidative stress. Abbreviations: Hcy, homocysteine; SAH, S-adenosylhomocysteine; SAM, S-adenosylmethionine; HM, homocysteine-methionine; CH, cholesterol; TG, triglyceride.
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Metabolic analysis and database mining strategy. A total of 324 metabolic genes were chosen from three systems: Hcy (119), glucose-related (95), and Lipid (66 for triglyceride and 44 for cholesterol metabolism) from the NCBI database. The mRNA expression patterns of these genes were analyzed across 21 human and 20 mouse organs using the NCBI Unigene EST database. Organs were categorized based on gene enrichment levels. Hcy metabolites were measured in 6 mouse organs (heart, liver, lung, kidney, spleen, and brain) using LC-ESI-MS/MS. Simple linear regression analysis was conducted to identify genes responsive to Hcy metabolites. The responsive genes were then utilized to identify corresponsive metabolic changes, construct protein-protein interaction networks, and identify organ-specific metabolic features related to Hcy metabolites. Finally, genetic-metabolic models were established for how Hcy metabolites contribute to metabolic reprogramming, crosstalk, and oxidative stress. Abbreviations: Hcy, homocysteine; SAH, S-adenosylhomocysteine; SAM, S-adenosylmethionine; HM, homocysteine-methionine; CH, cholesterol; TG, triglyceride.

Journal: Redox Biology

Article Title: SAH is a major metabolic sensor mediating worsening metabolic crosstalk in metabolic syndrome

doi: 10.1016/j.redox.2024.103139

Figure Lengend Snippet: Metabolic analysis and database mining strategy. A total of 324 metabolic genes were chosen from three systems: Hcy (119), glucose-related (95), and Lipid (66 for triglyceride and 44 for cholesterol metabolism) from the NCBI database. The mRNA expression patterns of these genes were analyzed across 21 human and 20 mouse organs using the NCBI Unigene EST database. Organs were categorized based on gene enrichment levels. Hcy metabolites were measured in 6 mouse organs (heart, liver, lung, kidney, spleen, and brain) using LC-ESI-MS/MS. Simple linear regression analysis was conducted to identify genes responsive to Hcy metabolites. The responsive genes were then utilized to identify corresponsive metabolic changes, construct protein-protein interaction networks, and identify organ-specific metabolic features related to Hcy metabolites. Finally, genetic-metabolic models were established for how Hcy metabolites contribute to metabolic reprogramming, crosstalk, and oxidative stress. Abbreviations: Hcy, homocysteine; SAH, S-adenosylhomocysteine; SAM, S-adenosylmethionine; HM, homocysteine-methionine; CH, cholesterol; TG, triglyceride.

Article Snippet: The mRNA expression patterns of these genes were analyzed across 21 human and 20 mouse organs using the NCBI Unigene EST database.

Techniques: Expressing, Tandem Mass Spectroscopy, Construct